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Ingredients, Designed Around Hair Biology

At Bomme, ingredients are not selected in isolation.

They’re chosen, combined, and formulated to work with hair biology, not against it.

Hair health is cumulative and delayed. That means the effectiveness of an ingredient depends not only on what it is, but how it’s delivered, what it’s paired with, and how consistently it’s used over time. Our formulations are designed to support the scalp environment and hair growth cycle through stability, not stimulation.

The BLH308 Botanical Complex

BLH308 is our proprietary botanical complex developed to support long-term scalp and follicle health.

It combines three botanicals—persimmon leaf, green tea leaf, and sophora fruit extracts—each selected for its role in supporting the biological conditions associated with healthier hair growth over time.

Rather than targeting surface-level symptoms, BLH308 was developed to help address underlying factors such as scalp inflammation, follicle stress, and the hair growth environment. The complex has been evaluated in human clinical studies and was named a 2026 C&T Allē Awards finalist in the Cosmetic Active: Hair/Scalp Treatments category.

BLH308 serves as the foundational active across the Bomme system, supporting hair health both externally and internally when used consistently.

How We Group Ingredients by Function

Instead of highlighting single “hero” ingredients, we design formulas around biological roles. Each ingredient is selected to support one or more of the following functional areas.

Scalp Environment Support

A stable scalp environment is essential for long-term hair health. These ingredients are selected to help calm irritation, support the scalp barrier, and reduce reactivity that can disrupt healthy hair cycles.

Examples include botanicals and soothing agents chosen for their role in maintaining comfort, balance, and scalp integrity over time.

A calmer scalp creates the conditions follicles need to function more predictably.

Follicle Function & Growth Cycle Support

Hair growth is regulated by internal biological signals, not surface stimulation. These ingredients are selected to support follicle function within the natural hair growth cycle, helping maintain conditions that allow follicles to remain in the growth phase longer.

This includes ingredients studied for their role in regulating inflammatory markers, supporting signaling pathways, and maintaining a healthier follicle environment.

Progress here is gradual—and often invisible at first—but foundational.

Hair Fiber Comfort & Daily Manageability

While hair growth begins at the scalp, daily experience matters for consistency. These ingredients are included to support softness, manageability, and reduced breakage, helping hair feel comfortable while deeper scalp-level processes take place.

Comfort supports routine adherence, which is essential for long-term results.

Why a System Matters More Than Any Single Ingredient

No single ingredient can “fix” hair health on its own.

Hair biology responds to patterns—how ingredients interact, how consistently they’re applied, and how they support the scalp and body together over time. That’s why Bomme formulas are designed as a complete system, rather than standalone solutions.

Ingredients matter.

Formulation matters.

Consistency matters most.

Key Botanical Ingredients

Below are the primary botanicals used in the BLH308 complex and across the Bomme system, selected for how they function together rather than in isolation.

Persimmon

Persimmon leaf extract (Diospyros kaki) is a botanical antioxidant studied for its anti-inflammatory properties. Rich in phenolic compounds and flavonoids, it has been evaluated for its role in supporting scalp comfort and helping protect against external stressors that can disrupt hair growth environments.

Green tea

Green tea extract (Camellia sinensis), derived from the same flowering plant used in green teas, is rich in catechins and antioxidants and has been studied for its potential role in protecting the scalp and hair from oxidative stress caused by environmental factors such as free radicals caused by pollutants, irritants, and sun exposure.

Sophora fruit

Sophora fruit extract (Sophora japonica), derived from the fruit of the Japanese pagoda tree, is valued for its antioxidant and soothing properties and has been studied for its role in supporting a balanced, healthy scalp environment.

Learn More About the Research

If you’d like to explore the clinical studies, biological mechanisms, and third-party validation behind our formulations—including the research supporting BLH308—you can visit our Research page.

Our approach is grounded in science, designed for long-term care, and built to work with the body’s timelines—not against them.

This page is for those who want to understand not just what’s in our formulas, but why it’s there.

Research & Supporting Studies

The following studies and clinical evaluations inform the development of the BLH308 complex and its key botanical components.

  1. Lee H, Kim E, Kim G, Jeong G. Persimmon leaf extract protects mice from atopic dermatitis by inhibiting T cell activation via regulation of the JNK pathway. Phytother Res. 2021;35(5):2545‐2556. [PubMed] [Google Scholar]
  2. Lee JS, Lee MK, Ha TY, et al. Supplementation of whole persimmon leaf improves lipid profiles and suppresses body weight gain in rats fed high‐fat diet. Food Chem Toxicol. 2006;44(11):1875‐1883. [PubMed] [Google Scholar]
  3. Kwon J, Park J‐E, Lee J‐S, et al. Chemical constituents of the leaves of Diospyros kaki (persimmon). Plants. 2021;10(10):2032. [PMC free article] [PubMed] [Google Scholar]
  4. Hossain A, Shahidi F. Persimmon leaves: nutritional, pharmaceutical, and industrial potential – a review. Plants Basel Switz. 2023;12(4). [PMC free article] [PubMed] [Google Scholar]
  5. Matsumoto M, Kotani M, Fujita A, et al. Oral administration of persimmon leaf extract ameliorates skin symptoms and transepidermal water loss in atopic dermatitis model mice, NC/Nga. Brit J Dermatol. 2002;146(2):221‐227. [PubMed] [Google Scholar]
  6. Li H, Do MH, Lee MJ, Oh SB, Cho SY, Jeong JM. Improvement of hair loss by a persimmon leaf, green tea, and Sophora fruit extract complex (BLH308). Kor J Med Crop Sci. 2022;30(4):247‐263. [Google Scholar]
  1. Li H, Do MH, Lee MJ, Oh SB, Cho SY, Jeong JM. Improvement of hair loss by a persimmon leaf, green tea, and Sophora fruit extract complex (BLH308). Kor J Med Crop Sci. 2022;30(4):247‐263. [Google Scholar]
  2. Kwon OS, Han JH, Yoo HG, et al. Human hair growth enhancement in vitro by green tea epigallocatechin‐3‐gallate (EGCG). Phytomedicine. 2007;14(7‐8):551‐555. [PubMed] [Google Scholar]
  1. Li H, Do MH, Lee MJ, Oh SB, Cho SY, Jeong JM. Improvement of hair loss by a persimmon leaf, green tea, and Sophora fruit extract complex (BLH308). Kor J Med Crop Sci. 2022;30(4):247‐263. [Google Scholar]
  2. Abd-Alla H. I., Souguir D., Radwan M. O. (2021). Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives. Archives pharmacal Res. 44, 903–986. 10.1007/s12272-021-01354-2 [DOI] [PMC] [PubMed]
  1. Ham S, Lee YI, Kim IA, Suk J, Jung I, Jeong JM, Lee JH. Efficacy and safety of persimmon leaf formulated with green tea and sophora fruit extracts (BLH308) on hair growth: A randomized, double-blind, placebo-controlled clinical trial. Skin Res Technol. 2023 Sep;29(9):e13448. doi: 10.1111/srt.13448. PMID: 37753679; PMCID: PMC10443189. [PubMed]
  2. P&K Skin Research Center in South Korea. July 2023.
  3. P&K Skin Research Center in South Korea. January 2025.

Patents pending United States18/280,178 | China202280017781.8 | Japan2023-555471

European Union22788282.6 | India202317059954 | Singapore11202308093P