Hair loss
Hair loss can have many causes, including genetics, hormonal changes, medical conditions, medications, stress, nutritional deficiencies, aging, and certain hair care practices. Genetics play a key role, with male and female pattern hair loss being among the most common hereditary types. Hormonal imbalances, such as those related to pregnancy, menopause, or thyroid conditions, may result in temporary or permanent hair loss. Medical conditions like alopecia areata and trichotillomania can also be contributing factors. Additionally, some medications, treatments like chemotherapy, and high levels of stress may lead to hair loss, as well as poor nutrition and age-related thinning.
It’s important to consult a healthcare professional or dermatologist for an accurate diagnosis and appropriate treatment options.
There are many different types of hair loss, each with various underlying causes.
- The most prevalent form is androgenetic alopecia (AGA), characterized by the progressive miniaturization of hair follicles due to the action of dihydrotestosterone (DHT), a potent androgen derived from testosterone via 5-alpha reductase. This condition is highly prevalent among both men and women experiencing hair thinning or balding.
- Another type, telogen effluvium (TE), involves an abnormal shift in the hair growth cycle, where a significant proportion of follicles prematurely transition from the anagen (growth) phase to the telogen (resting) phase, resulting in diffuse shedding. TE can be precipitated by physiological or environmental stressors such as alterations in diet, psychological stress, hormonal imbalances, or disturbances in sleep patterns.
- Alopecia areata, accounting for approximately 5% of cases, is an autoimmune condition in which lymphocytic infiltration targets hair follicle cells, mistaking them as foreign, resulting in acute inflammation and hair loss. Immunomodulatory treatments, such as corticosteroids or JAK inhibitors like Baricitinib, have shown efficacy in managing this condition.
- Additional forms of alopecia include seborrheic alopecia, which results from hyperseborrhea and excessive sebum production that can lead to inflammation and follicular obstruction. Anagen effluvium is a common form of hair loss induced by chemotherapeutic agents, where cytotoxic drugs target rapidly dividing cells, including those in the hair follicles. Thyroid-related alopecias, such as those resulting from hyperthyroidism or hypothyroidism, occur due to disruptions in thyroid hormone levels, which can alter the normal hair growth cycle and lead to diffuse thinning or shedding.
Our bodies possess a remarkable immune system that safeguards us against external threats, ranging from microbial infections—such as bacteria, fungi, viruses, and parasites—to high molecular weight substances like foreign materials. In response to these invaders, immune cells trigger a process known as the inflammatory response.
To understand the body's inflammatory response, consider a knife cut or a bee sting. These events often present with four classic signs: fever, pain, redness, and swelling. This response is a natural defense mechanism, designed to rapidly eliminate potential threats. During inflammation, immune cells release toxic substances—such as free radicals and bactericidal peptides—to destroy invading microbes, while phagocytic cells engulf and digest the pathogens. However, this “battle” can also cause collateral damage to surrounding tissues. Once the threat is neutralized, the body shifts gears, producing anti-inflammatory substances to suppress the response and initiate the healing process.
Inflammation can be classified into two types: acute and chronic. Acute inflammation arises quickly in response to injury or infection and typically resolves within a short period. In contrast, chronic inflammation develops gradually and persists over a longer duration, often resulting from ongoing exposure to a low-level irritant or an underlying condition.
In the case of hair loss, the hair follicles are affected by chronic inflammation. Hair loss is generally not linked to acute inflammation, as acute inflammation is a short-term, immediate response to injury or infection. During acute inflammation, there is a rapid influx of immune cells aimed at swiftly eliminating the threat and initiating the healing process. In contrast, chronic inflammation in hair follicles is more insidious, persisting over time and gradually impairing follicular function, leading to hair thinning or loss.
Hair loss is often associated with chronic inflammation, which involves a prolonged and sustained inflammatory response. Elevated levels of dihydrotestosterone (DHT) around hair follicles can stimulate the production of a cytokine called interleukin-6 (IL-6). IL-6 is a pro-inflammatory signaling molecule that activates an inflammatory response, which can damage the follicle cells responsible for hair growth. Individuals may sometimes experience a mild sensation of warmth or itching on the scalp, indicative of this ongoing inflammatory activity. This chronic inflammation can weaken hair follicles, leading to the production of thinner hair, increased hair shedding, and, in severe cases, the potential loss of entire follicles.
Unlike acute inflammation, which is a short-term response, chronic inflammation creates a prolonged adverse environment for hair follicles, contributing to gradual and persistent hair thinning rather than the temporary effects observed with acute inflammation.
Hair loss prevention strategies depend on the underlying causes. While hair loss due to genetic factors or aging is generally not preventable, hair loss related to non-genetic factors such as stress, poor nutrition, or lifestyle habits can often be mitigated. For these cases, certain steps can help reduce the risk:
- Find healthy ways to manage stress and anxiety.
- Reduce or stop smoking.
- Limit alcohol consumption, as it can lead to dehydration and inflammation.
- Prioritize high-quality sleep.
- Avoid foods that may contribute to hair loss, such as fried foods or those stored in containers that could be contaminated with endocrine-disrupting chemicals (e.g., bisphenol A, alkylphenol, styrene, phthalates, persistent organic pollutants, PCBs).
Additionally, maintaining a balanced diet rich in essential nutrients, practicing gentle hair care, avoiding harsh treatments, managing stress, and addressing underlying medical conditions promptly can support healthy hair growth. Early intervention and appropriate management of conditions like hormonal imbalances or scalp infections can also help prevent further hair loss. It's important to note that the effectiveness of these strategies can vary based on individual circumstances, so consulting a healthcare professional is advisable for personalized guidance.
Hair loss is a common condition among men, with approximately 50% experiencing some degree of hair loss by the age of 50. The onset can occur as early as the late teens or early 20s and typically becomes more pronounced with age. Androgenetic alopecia, or male pattern baldness, is the most prevalent cause of hair loss in men. However, other factors, including stress, certain medical conditions and treatments, and lifestyle habits, can also play a role in contributing to hair loss.
Hair loss in women is also relatively common, though it often manifests differently than in men. Women typically experience diffuse thinning across the entire scalp rather than localized balding. Female pattern hair loss (FPHL) becomes more common with age, affecting approximately 40% of women by the age of 50. However, hair loss can occur at any age due to various factors, including hormonal fluctuations (such as those during pregnancy or menopause), underlying medical conditions, stress, and genetic predisposition.
- Warm Water. Ensure the water temperature is just right—not too hot or cold. Hot water can open pores and increase the risk of inflammation.
- Gentle products. Use shampoos free from harsh ingredients like sodium lauryl sulfate (SLS). Surfactants and preservatives can irritate the scalp, so opt for hypoallergenic or fragrance-free alternatives if you suspect allergies to hair care products.
- Gentle Technique. Avoid vigorous scrubbing and use only your fingertips to gently massage and work shampoo into the scalp. Scratching with fingernails can trigger inflammation. Do not use your fingernails, as scratching can cause irritation and trigger inflammation.
- Let it sit. Allow the shampoo to sit on your scalp for at least one minute before rinsing to give it time to work effectively.
- Rinse Thoroughly. Ensure that all shampoo is completely rinsed out of your hair, as any leftover residue can irritate the scalp.
- Air dry. Allow your hair to dry naturally. If you need to use a hair dryer, use the cool setting, as hot air can contribute to scalp inflammation.
- Avoid Sleeping with Wet Hair: Going to bed with wet hair can increase the risk of scalp irritation and inflammation. Here are some potential issues:
- Infections: Prolonged moisture can create an ideal environment for fungal or bacterial growth, leading to conditions such as tinea capitis (scalp ringworm) or folliculitis (inflammation of hair follicles). This risk increases if the hair remains wet for extended periods and proper drying or hygiene is not maintained.
- Breakage: Wet hair is more susceptible to breakage and damage. Rubbing or scratching the scalp when hair is wet—such as with aggressive towel drying or using brushes or fine-toothed combs—can irritate the scalp and lead to inflammation. This is particularly problematic for those with sensitive skin or conditions like eczema or psoriasis.
- Worsening of Underlying Conditions: If you have chronic scalp conditions such as seborrheic dermatitis, psoriasis, or eczema, wet hair can aggravate symptoms. Moisture can disrupt the skin barrier, leading to flare-ups. If you have a chronic scalp condition, consult a dermatologist for a proper diagnosis and treatment plan. They can recommend specialized shampoos or treatments to help manage your symptoms effectively.
Root Renewal Supplements
Yes, Bomme’s active ingredients are potent antioxidants that have been clinically proven to address the chronic inflammation that can hinder hair growth.
In a 24-week clinical trial published in Skin Research & Technology, participants experienced significant improvements in hair density and thickness after consistently using our supplements for six months. Improvements were observed as early as 8 weeks, with more substantial improvements at 16 and 24 weeks.
Bomme’s Root Renewal Supplements are formulated with an innovative blend of persimmon leaf, green tea, and sophora fruit extracts. Persimmon leaf extract (PLE) helps protect cells from oxidative stress, thereby reducing inflammation. Green tea extract serves as a powerful antioxidant, promoting cell regeneration and regrowth. Sophora fruit extract supports vascular health by dilating blood vessels and enhancing circulation, while also offering anti-inflammatory benefits.
Mechanism of Action:
- Finasteride: Testosterone is converted into dihydrotestosterone (DHT) through the enzyme 5-alpha-reductase, which binds to testosterone at its active site, facilitating the conversion. DHT is a key factor in hair loss, particularly in androgenetic alopecia, as it can contribute to hair follicle miniaturization. Finasteride works by competing with testosterone for binding to the active site of 5-alpha-reductase, inhibiting the enzyme's ability to convert testosterone into DHT. This competitive inhibition results in reduced DHT levels, which may help slow or reverse hair loss. However, this approach directly alters the hormonal pathway by blocking the enzyme’s activity.
- Bomme: Unlike finasteride, Bomme does not inhibit 5-alpha-reductase through direct competition. Instead, Bomme works by reducing and normalizing the expression of 5-alpha-reductase in human follicle dermal papilla cells (HFDPCs). This approach may help maintain more balanced DHT levels without fully blocking its synthesis. By managing the overall presence of the enzyme, Bomme aims to support hair health without directly altering the enzymatic conversion process. This approach may help create a balanced environment for hair follicles without disrupting other hormonal functions.
Anti-Inflammatory Properties:
- Finasteride: While finasteride primarily targets the hormonal pathway, it does not directly address inflammation within the scalp. Its main role is reducing DHT levels to help prevent follicle shrinkage, which may indirectly reduce inflammation over time by decreasing DHT’s effects on hair follicles.
- Bomme: Bomme’s ingredients are intended to support hair health by reducing inflammation, specifically targeting pro-inflammatory cytokines like IL-6, which are associated with chronic inflammation and hair follicle miniaturization. This approach aims to create a healthier environment for hair follicles by addressing inflammation that may contribute to hair thinning and loss.
Side Effects and Safety:
- Finasteride: Finasteride has been shown to be effective in reducing DHT levels, but its impact on hormonal pathways can lead to potential side effects, including changes in sexual function such as decreased libido, erectile dysfunction, and reduced semen volume. Some users may also experience mood changes or other effects, including gynecomastia, rashes, or swelling. These side effects are linked to its influence on hormone levels.
- Bomme: Bomme aims to manage DHT levels through enzyme expression regulation rather than direct inhibition, which may reduce the risk of disrupting hormonal balance. By focusing on inflammation reduction and supporting healthy hair follicle function, Bomme’s approach may be considered as an alternative for those seeking to support hair health without the hormonal effects associated with certain medications. However, as with any supplement, individual responses may vary, and users are encouraged to consult with a healthcare provider before use.
Summary:
Finasteride and Bomme take different approaches to hair health. Finasteride directly inhibits the conversion of testosterone to DHT, making it a targeted treatment for androgenetic alopecia but with potential side effects due to hormonal changes. Bomme, in contrast, aims to support hair health by managing DHT levels indirectly and addressing inflammation through natural ingredients, providing an option for those seeking a more holistic approach. It’s important to note that the effectiveness of either product can vary between individuals, and consultation with a healthcare professional is recommended before starting any new regimen.
Bomme is formulated with natural ingredients intended for safe, long-term use, with no known side effects. While it is generally well-tolerated, individual experiences may vary, and we recommend consulting with a healthcare professional before starting any new supplement regimen.
Take two tablets per day on an empty stomach, ideally in the morning. For best results, continue taking the supplements consistently for 1 to 3 months to observe visible improvements.
Both! Our supplements and toners are designed to be effective for men and women alike.
No, Bomme supplements do not contain any drugs. They are made from natural, plant-based ingredients.
Bomme supplements have a shelf life of 3 years.
Yes, Bomme supplements are generally safe to use alongside other hair growth products. However, we recommend consulting with a healthcare professional before combining them with other treatments to ensure the best results and avoid any potential interactions.
If you are currently using minoxidil, it's important to know that stopping it abruptly could lead to hair shedding. We recommend gradually reducing minoxidil usage over several weeks or months as you transition to using Bomme products. It is also safe to continue using minoxidil while taking Bomme supplements, but for personalized guidance, consult with a healthcare professional before making any changes to your hair care routine.
Revitalizing Scalp Toner
Yes, Bomme’s Revitalizing Scalp Toner is effective. In a clinical study conducted by the P&K Skin Research Center in South Korea in 2023, participants experienced a significant improvement in hair density and thickness—up to 72%—after consistently using the Toner for just 4 weeks.
It’s for everyone! Bomme’s Revitalizing Scalp Toner is suitable for use by both men and women.
For best results, do not wash your hair immediately after applying the toner. Instead, allow your hair to dry naturally. If you need to wash your hair, do so before applying the toner, as it should be applied to a dry scalp.
The toner should be used daily for best results.
There have been no reports of harmful side effects associated with Bomme products. However, if you experience any unusual symptoms like redness, swelling, or itching, it’s important to consult a medical professional.
Yes, many customers use the product on color-treated or chemically processed hair without experiencing any adverse effects. However, as with any product, we recommend doing a patch test before full use to ensure compatibility with your hair type.
The Revitalizing Scalp Toner has a shelf life of 3 years.
Our company
In 2002, Dr. Jeong-Moon Jeong founded his research facility in South Korea with a mission to uncover the scientific mechanisms behind various diseases and to discover natural remedies specifically designed to address these mechanisms. As Dr. Jeong often said, “All diseases come from nature, and all remedies also come from nature.”
Dr. Jeong’s research turned to the causes of hair loss, focusing particularly on the role of inflammation. He hypothesized that by inhibiting the production of inflammatory cytokines like IL-6, and by reducing the production of dihydrotestosterone (DHT)—a molecule linked to hair loss—through the regulation of 5-alpha reductase, hair loss could be mitigated. His goal was to create a solution using high-quality plant extracts rather than chemical compounds. The search for the most effective natural ingredients took over a decade of dedicated research.
In 2015, Dr. Jeong discovered the key ingredients: Persimmon Leaf Extract (an antioxidant that protects cells from oxidative stress and reduces inflammation), Sophora Japonica Fruit Extract (an antioxidant that promotes cell proliferation, enhances circulation, and reduces inflammation), and Green Tea Extract (an antioxidant that supports cell regeneration). He and his team then worked diligently to determine the optimal ratios of these ingredients to maximize their therapeutic effects, leading to the creation of Bomme’s unique formulation.
Our products are formulated and produced in South Korea at an MFDS-certified (Ministry of Food and Drug Safety) facility.
Yes. Our products are rigorously tested for safety and efficacy.
In 2022, clinical trials were conducted to evaluate the effectiveness of our supplements and toners. The results of this human clinical study were published in 2023 in the internationally recognized scientific journal Skin Research & Technology. A randomized, double-blind, placebo-controlled clinical trial for Bomme’s Root Renewal Supplements (BLH308) demonstrated that participants experienced significant improvements in hair density and thickness after consistently taking the supplements for six months, with visible improvements at 8, 16, and 24 weeks.
Additionally, a clinical study conducted by the P&K Skin Research Center in South Korea in 2023 showed that participants using our Toner saw significantly improved hair density and thickness—up to 72%—after four weeks of consistent use.
Bomme’s active ingredients are backed by numerous scientific studies, further supporting their efficacy.
Pomegranate ingredient studies (6+)
- Lee H, Kim E, Kim G, Jeong G. Persimmon leaf extract protects mice from atopic dermatitis by inhibiting T cell activation via regulation of the JNK pathway. Phytother Res. 2021;35(5):2545‐2556. [PubMed] [Google Scholar]
- Lee JS, Lee MK, Ha TY, et al. Supplementation of whole persimmon leaf improves lipid profiles and suppresses body weight gain in rats fed high‐fat diet. Food Chem Toxicol. 2006;44(11):1875‐1883. [PubMed] [Google Scholar]
- Kwon J, Park J‐E, Lee J‐S, et al. Chemical constituents of the leaves of Diospyros kaki (persimmon). Plants. 2021;10(10):2032. [PMC free article] [PubMed] [Google Scholar]
- Hossain A, Shahidi F. Persimmon leaves: nutritional, pharmaceutical, and industrial potential – a review. Plants Basel Switz. 2023;12(4). [PMC free article] [PubMed] [Google Scholar]
- Matsumoto M, Kotani M, Fujita A, et al. Oral administration of persimmon leaf extract ameliorates skin symptoms and transepidermal water loss in atopic dermatitis model mice, NC/Nga. Brit J Dermatol. 2002;146(2):221‐227. [PubMed] [Google Scholar]
- Li H, Do MH, Lee MJ, Oh SB, Cho SY, Jeong JM. Improvement of hair loss by a persimmon leaf, green tea, and Sophora fruit extract complex (BLH308). Kor J Med Crop Sci. 2022;30(4):247‐263. [Google Scholar]
Green tea ingredient studies (2+)
- Li H, Do MH, Lee MJ, Oh SB, Cho SY, Jeong JM. Improvement of hair loss by a persimmon leaf, green tea, and Sophora fruit extract complex (BLH308). Kor J Med Crop Sci. 2022;30(4):247‐263. [Google Scholar]
- Kwon OS, Han JH, Yoo HG, et al. Human hair growth enhancement in vitro by green tea epigallocatechin‐3‐gallate (EGCG). Phytomedicine. 2007;14(7‐8):551‐555. [PubMed] [Google Scholar]
Sophora fruit ingredient studies (2+)
- Li H, Do MH, Lee MJ, Oh SB, Cho SY, Jeong JM. Improvement of hair loss by a persimmon leaf, green tea, and Sophora fruit extract complex (BLH308). Kor J Med Crop Sci. 2022;30(4):247‐263. [Google Scholar]
- Abd-Alla H. I., Souguir D., Radwan M. O. (2021). Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives. Archives pharmacal Res. 44, 903–986. 10.1007/s12272-021-01354-2 [DOI] [PMC] [PubMed]
Bomme clinical trials (2)
- Ham S, Lee YI, Kim IA, Suk J, Jung I, Jeong JM, Lee JH. Efficacy and safety of persimmon leaf formulated with green tea and sophora fruit extracts (BLH308) on hair growth: A randomized, double-blind, placebo-controlled clinical trial. Skin Res Technol. 2023 Sep;29(9):e13448. doi: 10.1111/srt.13448. PMID: 37753679; PMCID: PMC10443189. [PubMed]
- P&K Skin Research Center in South Korea. July 2023.
Shipping and returns
Currently, we ship within the United States and Canada. Shipping is complimentary for both regions; however, customers in Canada will be responsible for any customs-related charges. We plan to expand our shipping to Asia, Europe, and the Middle East in the future—stay tuned for updates!
We ship from our warehouse in Gardena, California.
Standard shipping is complimentary for all orders. A small fee applies for those who choose expedited shipping.
Once your order is placed, it takes 1-2 business days for processing, packaging, and preparation for shipping. After that, packages typically arrive within 3-7 business days.
You'll receive an email with tracking information once your order is shipped. If you don't see the confirmation email within a day, please check your "spam" folder before contacting us via email.
If you made any errors while entering your order, please contact us directly. We will do our best to correct the issue and ensure the accurate delivery of your order.
If you encounter any delivery issues, please contact us immediately at hello@bommehair.com and include a photo of any damaged items.
If your order hasn’t arrived within 3-7 business days from the shipping date (as indicated in your tracking information), or if there is an issue with your order, reach out to us as soon as possible.
Account and ordering
If you are not 100% satisfied with your purchase, you can return the product for a full refund or exchange within 30 days of the purchase date. Please ensure that any product you return is in the same condition as you received it and in its original packaging. To request a return, contact us at hello@bommehair.com.
Once we receive and inspect your return, we will notify you by email. This email will include the status of your return, including whether it has been approved or rejected. If approved, your refund will be processed, and a credit will automatically be applied to your credit card or original method of payment.